Reinforcement of injectable calcium phosphate cement by gelatinized starches

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Reinforcement of injectable calcium phosphate cement by gelatinized starches.

Current injectable calcium phosphate bone cements (CPC) encounter the problems of low strength, high brittleness, and low cohesion in aqueous environment, which greatly hinder their clinical applications for loading-bearing bone substitution and minimally invasive orthopedic surgeries. Here, a strategy of using gelatinized starches to reinforce injectable CPC was investigated. Four types of sta...

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Calcium phosphate cement (CPC) can be molded and self-hardens in vivo to form resorbable hydroxyapatite with excellent osteoconductivity. The objective of this study was to develop an injectable, macroporous and strong CPC, and to investigate the effects of porogen and absorbable fibers. Water-soluble mannitol was used as porogen and mixed with CPC at mass fractions from 0% to 50%. CPC with 0-4...

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Introduction of gelatin microspheres into an injectable calcium phosphate cement.

For tissue engineered bone constructs, calcium phosphate cement (CPC) has a high potential as scaffold material because of its biocompatibility and osteoconductivity. However, in vivo resorption and tissue ingrowth is slow. To address these issues, microspheres can be incorporated into the cement, which will create macroporosity after in situ degradation. The goal of this study was to investiga...

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CALCIUM PHOSPHATE CEMENT: STUDY OF (BETA-TRICALCIUM PHOSPHATE, DICALCIUM PHOSPHATE AND CALCIUM CARBONATE SYSTEM

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Reinforcement of calcium phosphate cement with multi-walled carbon nanotubes and bovine serum albumin for injectable bone substitute applications.

This paper presents the development of novel alternative injectable calcium phosphate cement (CPC) composites for orthopaedic applications. The new CPC composites comprise β-tri-calcium phosphate (β-TCP) and di-calcium phosphate anhydrous (DCPA) mixed with bovine serum albumin (BSA) and incorporated with multi-walled carbon nanotubes (MWCNTs) or functionalized MWCNTs (MWCNTs-OH and MWCNTs-COOH)...

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ژورنال

عنوان ژورنال: Journal of Biomedical Materials Research Part B: Applied Biomaterials

سال: 2015

ISSN: 1552-4973

DOI: 10.1002/jbm.b.33434